Thu. May 2nd, 2024
  • IIT Madras and IIT Mandi researchers modified plant cells to increase the production of anti-cancer drug camptothecin.
  • The anti-cancer drug camptothecin (CPT) is produced from an endangered plant named Nathapodytes nimmoniana.
  • Around 1,000 tonnes of plant material is required to produce 1 tonne of CPT.
  • The plant population has declined by 20% and it is on the red list of IUCN.
  • Researchers from the Plant Cell Technology Lab of IIT Madras have developed a genome-scale metabolic model for N. nimmoniana plant cells.
  • This research has been funded by the Science and Engineering Board (SERB) and the Department of Science and Technology.
  • This research could pave the way for the drug’s effective and efficient commercial production and reduce the need to cut down this endangered plant.

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